- Dr. Grosso will develop and implement the company's expanding clinical trial agenda.
- Tevogen's cell therapy research pipeline focuses on virology, neurology, and oncology.
- Tevogen is reported as the highest valued tech startup of 2022.
WARREN, N.J.–(BUSINESS WIRE)–#COVID19–Tevogen Bio, a late-stage clinical biotechnology company specializing in the development of cellular immunotherapies in virology, neurology, and oncology today announced the appointment of Dr. Grosso to lead the development and implementation of the company's expanding clinical trial portfolio.
Dr. Grosso has spent more than 40 years in health care, the first 15 years as a critical care nurse at Thomas Jefferson University in Philadelphia. She earned a Master of Science degree in 1986 and a Post Master's Nurse Practitioner degree in 1995, both in Critical Care Nursing, from the University of Pennsylvania. In 1996, she joined the Blood and Marrow Transplant Program as a Nurse Practitioner at Thomas Jefferson University.
Over the next 25 years, Dr. Grosso expanded her career in cellular therapy research under the mentorship of acclaimed oncologist, Professor Neal Flomenberg, M.D. In 2009, she earned a Doctor of Nursing Practice investigating donor selection strategies in haploidentical hematopoietic stem cell transplantation at Thomas Jefferson University. Later that year, she was appointed to the faculty of Jefferson Medical College, ultimately achieving the rank of Associate Professor in Research in early 2022. Dr. Grosso has written over 20 investigator-initiated research protocols with multiple first and last author publications. She has served as a research mentor to numerous physician fellows including several participating in a Master's in Pharmacology Program at Jefferson. In 2021, she won the prestigious Excellence in Clinical Research Award from the Sidney Kimmel Cancer Center at Thomas Jefferson University in recognition of her prolific research activities and contributions to the Cancer Center's clinical research efforts.
“After 40 years caring for patients, I highly value Tevogen Bio's commitment to developing next-generation affordable immunotherapies,” said Dr. Grosso, “As a researcher, I am excited to participate in the expansion of Tevogen's precision T cell platform for the novel treatment of disease.”
“Since our foundation in 2020, our advanced science and business models have led us to become one of the most successful start-up biotech companies. As Tevogen's founder, I am pleased to welcome Dr. Grosso's unique experience and unwavering passion to our leadership team,” said Tevogen CEO Dr. Ryan Saadi, M.D., M.P.H.
About Tevogen's Next Generation Precision T Cell Platform
Tevogen's next generation precision T cell platform is designed to provide increased immunologic specificity to eliminate malignant and virally infected cells, while allowing healthy cells to remain intact. Multiple targets are selected in advance with the goal of overcoming the mutational capacity of cancer cells and viruses which can otherwise allow for escape from immunologic targeting.
Tevogen is investigating its technology's potential to overcome the primary barriers to the broad application of personalized T cell therapies: potency, purity, production-at-scale, and patient-pairing, without the limitations of current approaches. Tevogen's goal is to open the vast and unprecedented potential of developing personalized immunotherapies for large patient populations impacted by common cancers and viral infections.
Tevogen announced the completion of patient enrollment in the Proof-of-Concept clinical trial of its lead product, TVGN-489, for ambulatory, acute-risk COVID-19 patients, with no dose-limiting toxicities or significant treatment-related adverse events observed for any patient at any dose level.
TVGN-489 is a genetically unmodified, off-the-shelf, allogeneic cytotoxic CD8+ T lymphocyte (CTL) product with activity against multiple, precise targets across the entire SARS-CoV-2 genome.
About Tevogen Bio
Tevogen Bio is driven by a team of highly experienced industry leaders and distinguished scientists with drug development and global product launch experience. Tevogen's leadership believes that accessible personalized immunotherapies are the next frontier of medicine, and that disruptive business models are required to sustain medical innovation in the post-pandemic world.
Forward Looking Statements
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